NFL picks, predictions, best bets today: This Week 13 computer parlay returns 25-1 – CBS Sports

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All four underdogs that have played in Week 13 have won outright thus far. Now the Week 13 NFL schedule continues on Sunday with 11 more games, followed by Patriots vs. Giants closing the curtain on the weekend on ‘Monday Night Football.’ The latest Week 13 NFL odds list three teams as underdogs of +9.5 or more — the Panthers (+10.5) vs. the Rams, the Vikings (+11.5) vs. the Seahawks and the Raiders (+9.5) vs. the Chargers.
Will the upset trend continue, and how should you approach some of the tighter NFL lines such as Colts (-3.5) vs. Texans, as C.J. Stroud returns after missing three games, Falcons (-2.5) vs. Jets and Bills (-3) vs. Steelers, with Aaron Rodgers back under center? Before locking in any Week 13 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.
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The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 13 on a 49-33 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.
Now, the model has scoured the Week 13 NFL odds and locked in five confident NFL best bets. If you successfully parlay its picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s Week 13 NFL picks at SportsLine.
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After simulating every game 10,000 times, the model is high on the Los Angeles Rams (-10.5, 45) to cover against the Carolina Panthers despite being the second-largest spread of the week. The Seahawks (8-3) are the only team with a larger spread at -10.5 over the Minnesota Vikings (4-7). 
The 9-2 Rams are the top seed in the NFC and have won six games in a row. Los Angeles is led by quarterback Matthew Stafford, who has thrown for 2,830 yards and 30 touchdowns with just two interceptions. 
The model has Los Angeles winning outright 75% of the time and covering in over 50% of simulations. See which other NFL parlay picks to make here, and bet the Rams to cover here:
The model also jumped on four other NFL matchups where it says the line is way off, including backing an underdog that it says will easily cover. You can only see the model’s Week 13 NFL best bets and NFL parlay at SportsLine.
What are the model’s top Week 13 NFL picks, and which NFL matchups should you target for an epic 25-1 payout? Visit SportsLine now to see the Week 13 NFL best bets from a model on a 49-33 run on top-rated picks, and find out.
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