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    NCAA tournament odds, picks, bracket: Opening betting lines, expert predictions for March Madness first-round games – Yahoo Sports

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    March Madness is here and the 2025 NCAA tournament bracket on both the men's and women's sides has been revealed. For the men's tournament, Duke, Florida, Houston and Auburn are the four No. 1 seeds, with Auburn grabbing the top overall seed. Florida is the betting favorite to cut down the nets with +350 odds at BetMGM, with Duke (+360) and Auburn (+400) right behind the Gators.
    The opening game of the men's First Four started with a bang on Tuesday as Alabama State slipped past St. Francis, 70-68, winning on a layup off a tipped full-court pass with a second left. Alabama State will now face No. 1 overall seed Auburn in the South region on Thursday. UNC followed that on Tuesday with an absolute blowout on fellow No. 11 seed San Diego State.
    [Full NCAA tournament bracket revealed | Printable bracket]
    For a deeper look at who might win the tournament — and who might pull off an early upset — our experts have made their picks, choosing the winner for each first-round matchup of the men's tournament.
    The clock is already ticking for you to fill out your bracket and join our Bracket Mayhem game, and the odds for every first-round March Madness games are already up at sportsbooks and moving, as bettors place their wagers. If you need any tips on bracket strategy, we also have you covered.
    [Yahoo Fantasy Bracket Mayhem is back: Enter for a shot to win up to $50K]
    Below you'll find the odds for every first-round game at BetMGM, including the First Four games on Tuesday and Wednesday, sorted by region.
    Tuesday
    No. 16 Alabama State (-3.5) vs. No. 16 St. Francis (PA) Alabama State 70, St. Francis 68
    No. 11 North Carolina (-3.5) vs. No. 11 San Diego State UNC 95, SDSU 68
    Wednesday
    No. 16 American University (-1.5) vs. No. 16 Mount St. Mary's
    No. 11 Xavier (-1.5) vs. No. 11 Texas
    No. 1 Duke vs. No. 16 Mount St. Mary's/American University
    No. 8 Mississippi State vs. No. 9 Baylor (-1.5)
    No. 5 Oregon (-4.5) vs. No. 12 Liberty
    No. 4 Arizona (-15.5) vs. No. 13 Akron
    No. 6 BYU (-3.5) vs. No. 11 VCU
    No. 3 Wisconsin (-17.5) vs. No. 14 Montana
    No. 7 St. Mary's (-5.5) vs. No. 10 Vanderbilt
    No. 2 Alabama (-22.5) vs. No. 15 Robert Morris
    No. 1 Houston (-27.5) vs. No. 16 SIU-Edwardsville
    No. 8 Gonzaga (-4.5) vs. No. 9 Georgia
    No. 5 Clemson (-7.5) vs. No. 12 McNeese State
    No. 4 Purdue (-10.5) vs. No. 13 High Point
    No. 6 Illinois vs. No. 11 Texas/Xavier
    No. 3 Kentucky (-10.5) vs. No. 14 Troy
    No. 7 UCLA (-5.5) vs. No. 10 Utah State
    No. 2 Tennessee (-19.5) vs. No. 15 Wofford
    No. 1 Auburn vs. No. 16 Alabama State
    No. 8 Louisville (-1.5) vs. No. 9 Creighton
    No. 5 Michigan (-3.5) vs. No. 12 UC San Diego
    No. 4 Texas A&M (-7.5) vs. No. 13 Yale
    No. 6 Ole Miss vs. No. 11 UNC/SDSU
    No. 3 Iowa State (-13.5) vs. No. 14 Lipscomb
    No. 7 Marquette (-3.5) vs. No. 10 New Mexico
    No. 2 Michigan State (18.5) vs. No. 15 Bryant
    No. 1 Florida (-28.5) vs. No. 16 Norfolk State
    No. 8 UConn (-4.5) vs. No. 9 Oklahoma
    No. 5 Memphis vs. No. 12 Colorado State (-3.5)
    No. 4 Maryland (-11.5) vs. No. 13 Grand Canyon
    No. 6 Missouri (-6.5) vs. No. 11 Drake
    No. 3 Texas Tech (-15.5) vs. No. 14 NC-Wilmington
    No. 7 Kansas (-5.5) vs. No. 10 Arkansas
    No. 2 St. John's (-17.5) vs. No. 15 Omaha
    Here's how Yahoo Sports' Frank Schwab thinks the opening games of the 2025 NCAA tournament will play out.

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